This study examines the relevance of informal socio-economic activities, such as inter-marriage and trade linkages, taking place between Nigeria and Niger border towns of Mai‟adua and Mai‟mujia in explaining key aspects socio economic well-being and peaceful co-existence of the people in the area. Specifically, attention is on the nature and dynamics of these relationship and the way they, either both or independently promote our understanding of the complexity attached to the politics of boundary relationships and to some extend national border security challenges. Moreover, the two border communities were once under a single entity except before boundaries were erected by colonial invasion. The study employs qualitative method using both primary and secondary data. In-depth interviews were conducted and information used to corroborate data collected from other sources such as documentary source in form of official documents, newspaper, government reports. Integration theory was adopted as the major framework of analysis. The empirical data examined indicated that inter-marriages and trade between the people of the two border communities of Mai‟adua and Mai‟mujia are encouraging the unity of the two nation–states of Nigeria and Niger Republics. This finding has some key implications on the extant literature. In particular, it has supported the long established tradition that poster cordial relationship between the two communities and their states. Based on this, the study, therefore, recommends for the improvement of these informal socio-economic activities as each or combination could enhance West African Regional Integration efforts already in place under the ECOWAS agenda. Equally, if properly harnessed, these factors would go a long way in enhancing Nigeria and Niger Republic relations especially in the establishment and maintenance of dry sea port.